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Product Details:
Payment & Shipping Terms:
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CAS: | 58-33-3 | Packing: | Aluminum Foil Bags Or As Requirement |
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Appearance: | White Powder | Purity: | Over 99% |
Grade: | Pharmaceutical Grade | MOQ: | 10g |
High Light: | Local Anesthetic Agents,Injectable Local Anesthetics |
Pharmacy Grade Drug Promethazine hydrochloride CAS: 58-33-3 for Reliving cough
Basic information:
Chemical name:Promethazine hydrochloride
MF:C17H21ClN2S
MW: 320.88
CAS:58-33-3
MOQ: 10g
Appearance: White or light yellow crystalline powder
Delivery methods: T/T, , Moneygram, Bitcoin
Delivery time: 4~7 working days.
COA:
Product name
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promethazine hydrochloride | |||
CAS No.
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58-33-3 |
Outer Packing
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25KG/DRUM | |
Production date
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APRIL 2016 |
Shelf life
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MARCH 2021 | |
Standard adopted
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IP | |||
Items of analysis
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Specification
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Results
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description | a white or faintly yellowish,crystalline powder | a white crystalline powder | ||
solubility | very soluble in water,freely soluble in chloroform and in ethanol(95%),practically insoluble in ether | very soluble in water,freely soluble in chloroform and in ethanol(95%);practically insoluble in ether | ||
A. IR absorption spectrum | positions and relative sizes of the banks in the spectrum of the sample and reference spectrum shall be concordant | positions and relative sizes of the bands in the spectrum of the sample and reference spectrum are concordant | ||
B.by TLC | It complies with the identification test for phenothiazines | it complies with the identification test for phenothiazine | ||
C.Test with nitric acid | forms orange colored solution and organge-red precipitate | complies with test for chlorides | ||
pH(10% w/v solution) | 4.0-5.0 | 4.31 | ||
isopromethazine | not more than 1.0% | less than 1.0% | ||
other impurity | not more than 0.5% | less than 0.5% | ||
sulphated ash | not more than 0.5% | 0.20% | ||
loss on drying at 105℃ | not more than 0.5% | 0.20% | ||
assay | 98.5-101%(on anhydrous basis) | 100.0% | ||
Conclusion
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Qualified
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What is promethazine hydrochloride?
Promethazine hydrochloride is a prescription drug. It’s available as an oral solution, a rectal suppository, and an oral tablet.
The rectal suppositories are available as the brand-named drugs Phenadoz, Phenergan, and Promethegan. They are also available as generic drugs. The oral solution and oral tablet are only available as generic drugs. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
Medical uses:
As a sedative
For preoperative sedation and to counteract postnarcotic nausea
To reduce nervousness, restlessness and agitation caused by psychiatric conditions (used for this purpose mainly in Europe)
As antiallergic medication to combat hay fever (allergic rhinitis), etc., or to treat allergic reactions, alone or in combination with oral decongestants such as pseudoephedrine
As an adjunct treatment for anaphylactoid conditions (IM/IV route preferred)
Together with codeine or dextromethorphan against cough
As a motion sickness or seasickness remedy when used with ephedrine or pseudoephedrine
To combat moderate to severe morning sickness and hyperemesis gravidarum: In the UK, promethazine is drug of first choice, being preferred as an older drug with which there is a greater experience of use in pregnancy (second in line being metoclopramide or prochlorperazine).
Previously, it was used as an antipsychotic,although it is generally not administered for this purpose now; promethazine has only approximately 1/10 of the antipsychotic strength of chlorpromazine.
Treatment for migraines; however, other similar medications, like Compazine, have been shown to have a more favorable treatment profile,and are used almost exclusively over promethazine.
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