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Local Anesthetic Agents,
Local Anesthetic Powder
High Purity and Moderate Price Bupivacaine Hydrochloride with reasonable price and fast delivery
Product Name: Bupivacaine
Synonyms: 1-Butyl-2 ', 6'-pipecoloxylidide; 1-Butyl-2- (2,6-xylycarbamoyl) piperidine; 1-Butyl- 1-butyl-2 ', 6'-pipecoloxylidide; 1-butyl-n- (2,6-dimethylphenyl) -2-piperidinecarboxamid
Product Categories: Active Pharmaceutical Ingredients
Mol File: 2180-92-9.mol
Usage: Infiltration anesthesia; nerve block anesthesia.
Indications for bupivacaine are local infiltration, peripheral nerve block, sympathetic block, and epidural and tail block. It is sometimes combined with adrenaline to prevent systemic absorption and prolong the duration of action. 0.75% (the strongest) formula used in the ball behind the block. It is the most commonly used local anesthetic during epidural anesthesia during labor, as well as postoperative pain management.
Local anesthesia is stronger than lidocaine (about four times stronger). The 0.25% ~ 0.5% solution caused by the time of local anesthesia is generally 4 to 10 minutes, 0.75% solution than the onset of slightly faster. With its 0.5% solution plus epinephrine for epidural anesthesia, the role can be maintained for 5 hours. As the goods in the blood concentration is low, the accumulation of the body less, the role of a long duration, it is safer for long-acting local anesthetic.
Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.
Bupivacainep, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours. Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate.
Bupivacaine is indicated for local anaesthesia including infiltration. Bupivacaine often is administered by epidural injection before total hip arthroplasty, Bupivacaine is also commonly injected to surgical.
Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.
Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
Bupivacaine is used as a local (in only one area) anesthetic.
Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.
Bupivacaine is also used as an anesthetic for dental procedures.
Bupivacaine may also be used for purposes not listed in this medication guide.
How Does Bupivacaine Work
The drug works by blocking the impulses of the nerves that transmit the sensation of pain. This includes impeding both the creation of nerve impulses and their ability to travel throughout the body. It does this specifically by binding to channels that carry sodium to the nerves, thus stopping their progress. Bupivacaine provides additional numbing by also blocking some potassium channels.
If it is administered incorrectly, bupivacaine can be cardiotoxic, which can result in damage to the muscles in and around the heart. The drug is not only ineffective when administered intravenously, but it has been known to be fatal. This is primarily because the drug does not work correctly when it is absorbed by the whole system instead of being administered locally. These risks are extremely low if the drug is injected as intended.
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