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Express: | TNT,DHL,Fedex, UPS, EMS, HKEMS, Etc. | CAS Number: | 73-78-9 |
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MF: | C14H23ClN2O | MW: | 270.7982 |
EINECS: | 200-803-8 | Melting Point: | 75 ~ 79 °C |
High Light: | Local Anesthetic Agents,Injectable Local Anesthetics |
99% Lidocaine Hydrochloride Local Anesthetic Powder / Pain Killer Drug CAS 73-78-9
Quick Details:
Lidocaine Hydrochloride
CAS:73-78-9
Synonyms:2-DIETHYLAMINO-N-(2'6'-DIMETHYLPHENYL)ACETAMIDE HCL;2-DIETHYLAMINO-N-[2,6-DIMETHYLPHENYL]ACETAMIDE HCL;ALPHA-(DIETHYLAMINO)-2',6'-ACETOXYLIDIDE HYDROCHLORIDE;A-(DIETHYLAMINO)-2 6-DIMETHYLACETANILIDE HYDROCHLORIDE;LIGNOCAINE HYDROCHLORIDE;LIDOCAINE HYDROCHLORIDE;LIDOCAINE HCL;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamidmonohydrochloride
Formula: C14H23ClN2O
Molecular Weight: 270.7982
EINECS:200-803-8
Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Research Chemical
Melting point: 75 ~ 79 °C.
Assay: ≥99%
Specifications: 25KG / drum
Appearance: White crystalline powder; Have slightly foul smell or special, bitter, white crystalline powder.
Prouduct COA:
Product Name | Lidocaine hydrochloride | ||||
Quantity | 1000kg | Batch No.20090705 | |||
MFG. Date | 20090705 | Analysis Date | 20090706 | ||
Exp. Date | 20120705 | Inspection Basis | EP5 | ||
ITEMS | SPECIFICATIONS | RESULTS | |||
Appearance | White crystalline powder | Pass | |||
Content Wt. | 99.00%-101.00% | 99.92% | |||
Identification | Chloridate | Positive | |||
Test A | Positive | ||||
Melting point | 74-79ºC | 76-78ºC | |||
Appearance of solution | Clear and colourless | Pass | |||
Water | 5.5-7.0% | 6.7% | |||
Acidity PH | 4.0-5.5 | 5.2 | |||
Sulphated ash | 0.10% max | 0.08% | |||
Heavy metals | 5ppm max | Pass | |||
2, 6-Dimethylaniline | 100ppm max | Pass | |||
Conclusion | Qualified |
Product description:
Local Anesthetic Drugs Lidocaine, also known as xylocaine and lignocaine , is a medication used to numb tissue in a specific area and to treat ventricular tachycardia . It can also be used for nerve blocks . Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer . When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours . Lidocaine may also be applied directly to the skin for numbing.
Common side effects with intravenous use include sleepiness, muscle twitching , confusion , changes in vision , numbness , tingling, and vomiting . It can cause low blood pressure and an irregular heart rate.There are concerns that injecting it into a joint can cause problems with the cartilage . It appears to be generally safe for use in pregnancy . A lower dose may be required in those with liver problems . It is generally safe to use in those allergic to tetracaine or benzocaine . Lidocaine is an antiarrhythmic medication of the class Ib type . Lidocaine works by blocking sodium channels and thus decreasing the rate of contractions of the heart . When used locally as a numbing agent, local neurons cannot signal the brain.
Local Anesthetic Drugs Lidocain was discovered in 1946 and went on sale in 1948 . It is on the WHO Model List of Essential Medicines , the most important medications needed in a basic healthcare system . It is available as a generic medication and is not very expensive . The wholesale cost in the developing world in 2014 was US$0.45 to $1.05 wholesale per 20ml vial of medication .
Applications:
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy . Therefore, lidocaine is suitable for infiltration , block , and surface anesthesia . Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias ; lidocaine , though , has the advantage of a rapid onset of action . Epinephrine vasoconstricts arteries , reducing bleeding and also delays the resorption of lidocaine , almost doubling the duration of anaesthesia . For surface anesthesia, several available formulations can be used for endoscopies , before intubations , etc . Buffering the pH of lidocaine makes local numbing less painful . Lidocaine drops can be used on the eyes for short ophthalmic procedures . There is tentative evidence for topical lidocaine for neuropathic pain.
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