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CAS Registry Number: | 434-03-7 | MF:: | C21H28O2 |
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Molecular Weight:: | 312.45 | Appearance: | White Or Milky White Crystalline Powder |
Purity: | 99% | Shipping Method: | Air&Sea Transporation,Express |
High Light: | Estrogen Blocker Steroids,Low Estrogen Steroids |
Safe 99%Top Quality Steroid Hormone Powder Ethisterone Powder CAS 434-03-7
What is Ethisterone?
Ethisterone (brand names Pranone, Progestoral, Lutocylol, Proluton C, many others), also known as 17α-ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is asteroidal progestin with androgenic activity which is derived from testosterone and was introduced for medical use in 1939. It was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (orsynthetic progestogen) to be introduced.Although ethisterone has largely been superseded by newer drugs and is now little used, it continues to be available in some countries.Moreover, the 19-nortestosterone progestins, such as norethisterone, are derived from ethisterone and are widely used ashormonal contraceptives and for other indications.
Specification
Name:Ethisterone
Synonyms:4,17ALPHA-PREGNEN-17BETA-OL-20-YN-3-ONE;4,17a-pregnen-17b-ol-20-yn-3-one;4,17A-PREGNEN-17B-OL-20-YNE;4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;(8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;ANHYDROHYDROXYPROGESTERONE;ANHYDROXYPROGESTERONE;17BETA-HYDROXY-4,17ALPHA-PREGNEN-20-YN-3-ONE
CAS: 434-03-7
MF:C21H28O2
MW:312.45
EINECS:207-096-5
Purity:99.5% min
Density: 1.13 g/cm3
Melting Point: 263-269 °C(lit.)
Boiling Point: 446.4 °C at 760mmHg
Flash Point: 190.2 °C
Appearance:White or milky white crystalline powder
MOQ: 10grams
Delivery: TNT/EMS/Hongkong EMS/Fedex/DHL
Ethisterone Application
The first orally active progestin, ethisterone (pregneninolone, 17α -ethynyltestosterone or 19-norandrostane), the 17α -ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U. S. In 1945 as Pranone.
Ethisterone was also marketed in the U. S. From the 1950s into the 1960s under a variety of trade names by other pharmaceutical companies that had been members of the pre-World War II European hormone cartel (Ciba, Organon, Roussel).
Ethisterone Dosage
Alkyne progesterone is orally active progestin, similar to its role and progesterone, can make the proliferative endometrium into secretory phase, and to promote breast development.
Injection of progesterone progestin activity equivalent to 1/5 of the oral 15 times stronger than the latter; and androgenic effects as small as 1/10 of testosterone.
This product is also easily absorbed from the oral mucosa, so sublingual use it effectively.
Also used to prevent threatened abortion and habitual abortion, but because of the maintenance of pregnancy are less effective, the effect is not good, such as the estrogen ethinyl estradiol combination is good effect.
COA
Product name | Ethisterone | |
Appearance | White crystalline powder | |
Water | ¡Ü3% | pass |
Assay | 98 .0~ 102.0% | 99.50% |
Loss on drying | ¡Ü0.5% | 0.20% |
Related substances | total impurities ¡Ü1.0% | Pass |
any individual impurity ¡Ü0.5% | Pass | |
Residual solvents | ethanol ¡Ü0.5% |
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FQA
ANTI-ESTROGEN | |
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