Selective Androgen Receptor Modulators Clomid Clomiphene Citrate Powder CAS 50-41-9

Selective Androgen Receptor Modulators Clomid Clomiphene Citrate Powder CAS 50-41-9

Quick Details:

Clomifene citrate is a drug treatment that stimulates your ovaries to release eggs.
Ovulation stimulation using clomifene citrate is a well-established, effective treatment (Brown et al 2009). Clomifene citrate is the most widely used of all fertility drugs.

Product name Clomifene Citrate
Alias: serophene; pergotime; clomphid; Clomid

Another name: 2-4-[2-Chloro-1,2-diphenylethenyl]phenoxy-N,N-diethylethanamine citrate
CAS register number 50-41-9

Appearance: white or milky white crystalline powder. Melting point 116.5-118, slightly soluble in ethanol, chloroform, water, insoluble in ether.
EINECS 200-035-3
Molecular formula C32H36ClNO8
Molecular weight 598.08

Usage: the goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases.

Synonyms: Clomiphene Citrate;clomifene citrate;clomphid;clomid;Fertyl;clomivid;Fertivet;anti estrogen hormones;Chloramiphene; serophene; pergotime; clomphid; Clomid

Storage:Store at 8℃-20℃, protect from moisture and light.

2D-Structure:

COA:

Applications:

Clomifene citrate is a recommended treatment for ovulation disorders caused by problems such as polycy

stic ovaries or polycystic ovary syndrome (NCCWCH 2013:18). It may be used on its own or in combinatio

n with another drug called metformin, which you take daily in several doses (NCCWCH 2013:147-8). It used to

be used in some cases of unexplained infertility. However, it's no longer recommended for thi

s, as there's a lack of evidence that it makes any difference compared to trying to get pregnant naturally (

Hughes et al 2010, NCCWCH 2013:18).

Clomifene citrate may also be used in cases of unexplained infertility (NCCWCH 2004: 58), although there'

s a lack of evidence that it really helps (Hughes et al 2010). Clomifene citrate blocks the effect of the horm

one oestrogen in your body. This blocking effect tricks your body into bumping up levels of two other horm

ones that are essential for ovulation. These two other hormones are:

follicle-stimulating hormone (FSH)

luteinising hormone (LH)

FSH causes the eggs in your ovaries to ripen, ready for release. LH triggers the release of one or more m

ature eggs from the ovary follicles. The egg or eggs then move down into one of your fallopian tubes.

1. What is clomifene citrate?

Clomifene citrate is a drug treatment that stimulates your ovaries to release eggs.
Ovulation stimulation using clomifene citrate is a well-established, effective treatment. Clomifene citrate is the most widely used of all fertility drugs.
Other drugs that may be used to treat ovulation disorders include metformin and bromocriptine.

2. What's the success rate of clomifene citrate?

About 70 per cent of women will ovulate in response to a fairly low dose of clomifene citrate. Of those who ovulate, about 40 per cent will become pregnant.
Other factors that can affect the pregnancy rate include:
the time in your cycle that you have sex
your age and weight
the count, shape, speed and motility (ability to move) of your partner's sperm

A low dose of clomifene may not be enough. Your doctor may increase the dose to help you conceive. Studies suggest that about 29 per cent of women who start taking the drug go on to have a live birth.

3. How does clomifene citrate work?

Clomifene citrate blocks the effect of the hormone oestrogen in your body. This blocking effect tricks your body into bumping up levels of two other hormones that are essential for ovulation. These two other hormones are:
1. follicle-stimulating hormone (FSH)
2. luteinising hormone (LH)
FSH causes the eggs in your ovaries to ripen, ready for release. LH triggers the release of one or more mature eggs from the ovary follicles. The egg or eggs then move down into one of your fallopian tubes.

4. How long will I have to take clomifene citrate for?

You usually take clomifene in pill form for five days early in your cycle, for up to six months at a time. A low dose of 50 mg is often used to start with.
1). If you have regular cycles, you'll start taking the pills within five days of your period starting, preferably on about day two.
2). If you're not menstruating at all or if your cycle is very irregular, your doctor will check that you're not pregnant. She'll then give you a synthetic version of the hormone progesterone, a progestogen called Provera.
3). Progesterone works with oestrogen to keep your reproductive cycle regular. Provera will re-establish your periods. Once you're having periods, you can then start taking clomifene citrate.
4). Ovulation generally occurs between five days and nine days after you've taken your last pill. Your fertility specialist may monitor your ovaries using ultrasound, at least during the first cycle. She'll look to see how your ovaries are responding and whether one egg follicle or more is preparing to release a mature egg into one of your fallopian tubes.
5). You might ovulate and conceive in the first month of taking clomifene citrate. Or it can take a month or two of drug therapy for you to start ovulating regularly.
6). Treatment may be continued for up to six cycles, as this is thought to be long enough to see whether your body is responding to the drug.

5. How to take clomid? effective cycle of clomid?

Clomid can be initiated at a dose of 50 mg daily for 5 days, starting on cycle day 3, 4, or 5 (where cycle day 1 is the first day of the menstrual period), thus being taken on cycle days 3-7, 4-8 or 5-9. During a clomifene-induced cycle, there should be frequent intercourse (every other day) the week before and including the estimated day of ovulation, (cycle days 9-18). If LH surge detection tests are used, these tests should be started 3 to 4 days after the last clomifene tablet is taken (that is, if taking clomifene on cycle days 4-8, LH surge tests should be started on cycle day 11) and continue until ovulation is indicated (that is, the test becomes positive.) or through cycle day 18. If there is no spontaneous surge, there may be an artificial triggering of oocyte release if there is an ovarian follicle of over 20 mm in size, such as by an intramuscular injection of 10,000 units of hCG.However, routinely using oocyte release triggering with hCG appears to decrease pregnancy chances compared to frequent monitoring with LH tests.

6. How is clomid vs nolvadex?

1) Clomid, however, is much weaker than Nolvadex in a mg for mg comparison, with roughly 150mgs of Clomid being equal to 20mgs of Nolvadex. It should be noted, however, that 150mgs of Clomid will still raise testosterone levels to approximately 150% of baseline value
You don′t have to use 150mgs, however; in my research, I′ve found that doses as low as 50mgs will show improvements and elevations in testosterone levels
In fact, my original Post-Cycle-Therapy regime (as suggested by Dan Duchaine in the original Underground Steroid Handbook) was 100mgs per day for a week and 50mgs/day for a week. Don′t laugh& for the late 90′s, when most anabolic steroid users didn′t even know how to use Clomid, it was considered a "state of the art" PCT routine. I suspect that Duchaine originally introduced this compound to the steroid using community.

2) Clomid, just like Nolvadex, is very safe for long term treatment of lowered testosterone levels (2), with some studies showing its safety and efficacy for up to four months. And post-cycle, when steroid users are suffering form lowered testosterone levels, is when Clomid is most effective.

Clomid Cycles & Doses

Clomid can be safely used for long periods of time as its adverse effects are not only mild but extremely rare. Some performance athletes will use Clomid throughout a steroid cycle to combat aromatizing effects as we discussed but aromatase inhibitors and Nolvadex are all far more common for this purpose. Even so, a mild dose of 25mg per day may be enough to combat the side-effects you are trying to stave off but again, for the sake of efficiency an aromatase inhibitor will prove to be far more valuable for this purpose.

As PCT is the most optimal time to use Clomid it is here where we will be most concerned with dosing and duration. Most will find a PCT period of approximately 4 weeks to be sufficient with 3 weeks of the total therapy including Clomid. A quality PCT will generally begin with approximately 10 days of hCG use with Clomid or Nolvadex to follow. Many athletes have successfully completed the PCT period by following their hCG use with one week of Clomid at 150mg per day followed by 2 weeks at 100mg per day. However, for some this will not prove to be enough and another week of approximately 50-100mg may be needed.

Clomid & Nolvadex

Clomid and Nolvadex (Tamoxifen) are commonly associated together and this is for all intense purposes very accurate. Both Clomid and Nolva as it is commonly known belong to the SERM class of medications and both serve to provide the same benefits by the same mode of action while on cycle, as well as during PCT. The largest difference and really the only one of any significance as it pertains to the subject matter here is in regards to potency. Milligram for milligram Nolva is much stronger thanClomid, nearly 8 times as strong; that’s a pretty big difference. For this reason, if a steroid user is going to use Clomid for any purpose he will necessarily need to use far more Clomid than he would if he were using Nolvadex.

Cook Recipes:

1 gram of Clomiphene Citrate
1 beaker suitable for holding the volume of liquids
7.6 ml of Glycerol
11.3 ml of 190 Proof Grain Alcohol

Clomid
Powder: per 1 gram of Clomiphene Citrate
Produces: Highest concentration made - 50 mg/ml

Requirements:

1 gram of Clomiphene Citrate
1 beaker suitable for holding the volume of liquids
8.4 ml of PEG 600
10.5 ml of 190 Proof Grain Alcohol

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