Dental Treatment Injectable Local Anesthetics Drugs Prilocaine CAS 721-50-6

Dental Treatment Injectable Local Anesthetics Drugs Prilocaine CAS 721-50-6

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

1. Quick Details:

2. Description of Prilocaine :

Prilocaine is local anesthetic used to numb a person’s skin and tissues. This medication is often made available as a cream that is topically applied, but it may also be available in an injectable form, which should always be administered by a specially trained professional. Its effects are not instant, but once a person experiences the associated numbness it may last for hours. During this time, it is important for a person to heed her health care provider’s advice so that she may avoid injuring herself.

Health care providers use prilocaine to dull the feeling in areas where they will administer injections or conduct certain procedures. This medication is considered a local anesthetic because it is generally applied to the area where it is needed. For example, if a dentist were using it, he would likely inject the medication into the gums near the site of his work area.

In addition to its injectable form, this medication is also available as a cream. The cream is applied topically to a specific area. It may require more time to take effect than an injection, and its effects may be more limited. In either case, once the numbness begins it may continue for hours.

3. How to Use Lidocaine/ Prilocaine Cream:

Use lidocaine/prilocaine cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with lidocaine/prilocaine cream. Talk to your pharmacist if you have questions about this information.

• Wash and completely dry the area to be treated. Apply a thick layer of cream to the affected skin. Do not rub lidocaine/prilocaine cream into the skin.
• Lidocaine/prilocaine cream should only be used on normal, unbroken skin. Do not apply to damaged skin.
• Avoid getting lidocaine/prilocaine cream in your eyes, nose, or mouth. If you get lidocaine/prilocaine cream in your eyes, rinse them with plenty of water.
• Wash your hands immediately after using lidocaine/prilocaine cream.
• Discard unused medicine and packaging in the trash, out of the reach of children and away from pets.
• If you miss a dose of lidocaine/prilocaine cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use lidocaine/prilocaine cream.

4. Application :

Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.

Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.

Prilocaine topical may also be used for other purposes not listed in this medication guide.

For a variety of surgical epidural block and infiltration anesthesia.
Prilocaine topical is a local anesthetic (numbing medication).It works by blocking nerve signals in your body.Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.

Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.

5. Usage and Dosage:

Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.

6. Other Topical Pain Relief Powders :

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