CAS 2180-92-9 Local Anesthetic Drugs , Local Anesthetic Agents Bupivacaine USP32 Certification

CAS 2180-92-9 Local Anesthetic Drugs , Local Anesthetic Agents Bupivacaine USP32 Certification

1. Quick Details:

2. Bupivacaine Description:

Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.

Bupivacainep, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours. Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate.

3. Bupivacaine Application:

• Bupivacaine is indicated for local anaesthesia including infiltration. Bupivacaine often is administered by epidural injection before total hip arthroplasty, Bupivacaine is also commonly injected to surgical.
• Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
• Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.
• Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
• Bupivacaine is used as a local (in only one area) anesthetic.
• Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.
• Bupivacaine is also used as an anesthetic for dental procedures.
• Bupivacaine may also be used for purposes not listed in this medication guide.

4. How Does Bupivacaine Work?

The drug works by blocking the impulses of the nerves that transmit the sensation of pain. This includes impeding both the creation of nerve impulses and their ability to travel throughout the body. It does this specifically by binding to channels that carry sodium to the nerves, thus stopping their progress. Bupivacaine provides additional numbing by also blocking some potassium channels.

If it is administered incorrectly, bupivacaine can be cardiotoxic, which can result in damage to the muscles in and around the heart. The drug is not only ineffective when administered intravenously, but it has been known to be fatal. This is primarily because the drug does not work correctly when it is absorbed by the whole system instead of being administered locally. These risks are extremely low if the drug is injected as intended.

5. How to Use Bupivacaine in Dextrose Solution:

Use bupivacaine in dextrose Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Bupivacaine in dextrose Solution is usually given as an injection at your doctor's office, hospital, or clinic.
If you miss a dose of bupivacaine in dextrose Solution, contact your doctor right away.
Ask your health care provider any questions you may have about how to use bupivacaine in dextrose Solution.

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