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|Appearance:||White Crystalline Powder||MF:||C29H53NO5|
|MW:||495.73||Alias:||Orlistat; Tetrahydrolipstatin; Xenical; Alli; Orlipastat|
|CAS:||96829-58-2||Usage:||Weight Loss Drug|
Fat Loss Steroids,
Weight Loss Steroids
CAS 96829-58-2 Fat Loss Injections Steroids Orlistat Tetrahydrolipstatin Alli
Orlistat is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name Xenical by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
Chemical Names: Orlistat; Tetrahydrolipstatin; Xenical; Alli; Orlipastat
Molecular Formula: C29H53NO5
Molecular Weight: 495.745 g/mol
History of Alli:
Despite the fact that orlistat has been commercialized in the US since 1999, Alli was only approved by the FDA in 2007. Since it has half the amount of orlistat than Xenical, it is a less aggressive treatment and may also be used by overweight patients, instead of just obese ones. It is currently the only OTC using orlistat as main ingredient. Alli gained the positive opinion of the FDA, but in 2010, the agency altered the medication’s safety recommendation after cases of severe liver injury in patients treated with orlistat. Another controversial moment marked the history of Alli when in 2014, GlaxoSmith Kline had to withdraw it from the U.S. market due to tampered packages.
Usages of Orlistat:
Orlistat is combined with a reduced-calorie diet to promote weight loss.
Orlistat also may be used to prevent weight gain after weight has been lost.
Candidates for treatment with orlistat are patients who are obese with a body mass index (a measure of obesity) of more than 30 kg/m2.
Candidates also include patients with a body mass index of between 27 and 30 kg/m2 if other risk factors for arteriosclerosis are present such as high blood pressure, diabetes, and elevated blood cholesterol or triglycerides.
Based on several scientific studies, the average weight loss that is achieved when orlistat is taken as recommended for six months to one year is 12.4 to 13.4 pounds.
How It Works:
Orlistat is a medicine that can help you to lose weight if you are obese or overweight. It works by interfering with the way fat is digested and absorbed by your body. It prevents the action of enzymes found in the digestive juices of your stomach and small intestine. These enzymes normally break down the fat which you consume in your diet and allows it to be absorbed into your bloodstream. By blocking the enzymes' action, orlistat reduces the digestion of fat. This allows the fat you have eaten to be passed out of your body instead of being absorbed by your body, and this helps you to lose weight.
How toTake Alli?
Alli comes in capsule form. It’s taken by mouth three times a day, either with a meal that contains a little bit of fat, or up to one hour afterward. If you eat a no-fat meal, your doctor may tell you to skip your dose. Never take more medicine than recommended.
It’s important to follow a low-calorie, low-fat diet while taking this medication. If you eat a lot of fatty foods, even just one high-fat meal like a greasy burger, you’re more likely to have uncomfortable digestive side effects. Choose lean cuts of meat and low-fat dairy products. In general, no more than 30% of your calories at each meal should come from fat.
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