Anti Cancer Bodybuilding Anabolic Steroids CAS 33069-62-4 Taxus Chinensis Extract Aclitaxel Taxol

Anti Cancer Bodybuilding Anabolic Steroids CAS 33069-62-4 Taxus Chinensis Extract Aclitaxel Taxol

Paclitaxel is an injectable medication that’s infused into your vein. It’s used to treat certain types of cancers, including ovarian, breast, and lung cancers and Kaposi’s sarcoma.Paclitaxel has emerged as an important agent in the treatment of breast cancer. The efficacy and tolerability of this agent, as well as its lack of cross-resistance with anthracyclines, have spurred intensive clinical investigation worldwide. Optimization of paclitaxel dose and scheduling and evaluation of the drug in combination regimens are a central focus of investigations.

1. Quick Details:

2. Description of Paclitaxel:

Paclitaxel is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.Paclitaxel is classified as a "plant alkaloid," a "taxane" and an "antimicrotubule agent."

Paclitaxel use is generally associated with manageable toxicity. Neutropenia and peripheral neuropathy are common clinical side effects of paclitaxel . The most common dose-limiting toxicity of paclitaxel, neutropenia, is both dose- and schedule-dependent. Severe neutropenia is typically of short duration and rarely associated with other hematologic toxicities. Cumulative peripheral neurotoxicity is typically mild and often reversible.

Hypersensitivity reactions are almost completely prevented by the use of a premedication regimen consisting of corticosteroids, cimetidine or ranitidine, and diphenhydramine.

3. How Paclitaxel Is Given:

Paclitaxel is given as an injection or infusion into the vein (intravenous, IV).

Paclitaxel is an irritant. An irritant is a chemical that can cause inflammation of the vein through which it is given. If the medication escapes from the vein it can cause tissue damage. The nurse or doctor who gives Paclitaxel must be carefully trained. If you experience pain or notice redness or swelling at the IV site while you are receiving Paclitaxel, alert your health care professional immediately.

Because severe allergic reactions have occurred in some people taking Paclitaxel, you will be asked to take medications to help prevent a reaction. Your doctor will prescribe the exact regimen.

Paclitaxel is given over various amounts of times and in various schedules.

There is no pill form of Paclitaxel.

The amount of Paclitaxel and the schedule that it is given will receive depend on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

4. How Paclitaxel Works:

Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).

Paclitaxel belongs to a class of chemotherapy drugs called plant alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents. The podophyllotoxins are derived from the May Apple plant. Camptothecan analogs are derived from the Asian "Happy Tree" (Camptotheca acuminata). Podophyllotoxins and camptothecan analogs are also known as topoisomerase inhibitors. The plant alkaloids are cell-cycle specific. This means they attack the cells during various phases of division.

5. How to Take Paclitaxel (Dosage) :

Injectable Solution:

Your doctor will determine a dose that’s right for you based on your individual needs. Your general health may affect your dose. Tell your doctor about all health conditions you have before your doctor or nurse administers the drug to you.

Your dose is determined by your body surface area and the type of cancer that you’re being treated for. Body surface area is calculated using your height and weight, so your dose is individualized for you.

The drug may be used as a single agent, as sequential therapy, or in combination with other chemotherapy agents and immunologic agents. Therapy on weekly and every-three-week schedules has been effective.

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