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CAS: | 50-02-2 | EINECS: | 200-003-9 |
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MF: | C22H29FO5 | MW: | 392.46 |
FP: | 297.5 °C | BP: | 568.2 °C At 760 MmHg |
Usage 1: | Anti-Inflammatory | Usage 2: | Pharmaceutical Raw Material |
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Pharmaceutical Raw Materials Anti Inflammatory Steroids Dexamethasone CAS 50-02-2
Dexamethasone is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders, and certain cancers. It is also used as a test for an adrenal gland disorder (Cushing's syndrome).This medication is a corticosteroid hormone (glucocorticoid). It decreases your body's natural defensive response and reduces symptoms such as swelling and allergic-type reactions.
1. Quick Details:
Product name: | Dexamethasone |
CAS: | 50-02-2 |
EINECS: | 200-003-9 |
Molecular formula: | C22H29FO5 |
Molecular weight: | 392.46 |
Melting point: | 262-264 °C(lit.) |
Flash Point: | 297.5 °C |
Boiling Point: | 568.2 °C at 760 mmHg |
Alpha: | 75 º (c=1, dioxane) |
Storage Temperature: | 2-8°C |
Water Solubility: | 10 mg/100 mL (25 ºC |
Appearance: | White crystalline solid |
2. Description:
Dexame-thasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone is also used to treat certain types of cancer.
Dexame-thasone comes as a tablet and a solution to take by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dexamethasone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
3. Application of Dexamethasone :
Dexamethasone wide range of applications, the role of strong, significantly, is commonly used corticosteroids, in the rescue of allergic diseases, shock, and other severe acute endocrine crisis have played a key role, is indispensable clinical drugs. Dexamethasone anti-inflammatory effects and control skin allergy stronger than prednisone, its anti-inflammatory activity equivalent to 0.75mg 5mg prednisone, skin allergies better. For status asthmaticus critical situation of the disease, it may be a good short-term high-dose intravenous dexamethasone effects, intravenous infusion every 5 ~ 20mg, 4 ~ 6h can be repeated dosing, reduction after 48 ~ 72h, 5 ~ 7 days withdrawal. Patients with cerebral edema due to various reasons can be given for the first time 10mg intravenous injection. Every 4 to 6 hours after intramuscular injection of 2 ~ 4mg, generally can be alleviated within 24h, 48 ~ 72h reductions, 7 days withdrawal.
4. What This Drug Is Used for:
As an anti-inflammatory medication. Dexamethasone relieves inflammation in various parts of the body. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain, and to treat eye inflammation.
5. How Should I Take Dexamethasone?
Take dexamethasone exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Your steroid medication needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using dexamethasone.
Do not stop using dexamethasone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.
Wear a medical alert tag or carry an ID card stating that you take dexamethasone. Any medical care provider who treats you should know that you are using steroid medication.
Store at room temperature away from moisture and heat.
6. COA:
Product name | Dexamethason E | |
Appearance | White crystalline powder | |
Specific optical rotation | Between+72°and +80° | +76.4° |
Chromatographic purity | Any individual impurity not more than 1.0% Total impurities not more than 2.0% | 0.46% 1.13% |
Loss on drying | Not more than 0.5% | 0.11% |
Residue on ignition | Not more than 0.2% | 0.06% |
Residual solvents | Methanol¡Ü3000ppm Methylene Chloride¡Ü600ppm Chloroform¡Ü60ppm Tetrahydrofuran¡Ü720ppm | 364ppm Not detect out Not detect out Not detect out |
Assay | Between 97.0% and 102.0% | 98.1% |
Micronixation | 90% not more than 10 microns | 90% not more than 10 aicrons |
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Peptide List |
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Product Name | Specification |
ACE 031 | 1 mg/vial, 10 vials/kit |
Follistatin 315 | 1 mg/vial, 10 vials/kit |
Follistatin 344 | 1 mg/vial, 10 vials/kit |
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MGF | 2 mg/vial, 10 vials/kit |
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Injectable Steroid Liquid :
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Tren Ace | 100mg/ml |
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Primobolan | 100mg/ml |
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Ripex 225 | 225mg/ml |
Tri Tren180 | 180mg/ml |
Tri Test 300 | 300mg/ml |
Tri Deca 300 | 300mg/ml |
Test Blend 450 | 450mg/ml |
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Mass 500 | 500mg/ml |
Cut Depot 400 | 400mg/ml |
Tren Test 225 | 225mg/ml |
Nandro Test Depot 450 | 450mg/ml |
EQ Test 450 | 450mg/ml |
Rip Cut 175 | 175mg/ml |
Tren Test Depot 450 | 450mg/ml |