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|Appearance:||White Crystalline Powder||Storage Condition::||2-8°C|
Estrogen Blocker Steroids,
Low Estrogen Steroids
CAS 54965-24-1 Nolvadex Tamoxifen Citrate For Recurrent Breast Cancer / Ovarian Cancer
Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
1. Quick Details:
|Product name:||Tamoxifen Citrate,Nolvadex|
|Melting point:||140-144 °C|
|Appearance:||White crystalline powder|
|Packing:||25KG/Drum or as per your requirements|
2. What Is Tamoxifen Citrate?
Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow.
Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).Tamoxifen may also be used for purposes not listed in this medication guide.
Tamoxifen Citrate (Nolvadex)is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine (anti-estrogen) therapy forhormonereceptor-positivebreast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.
is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
4. Tamoxifen Citrate Dosage:
The average Nolvadex dosage can vary quite dramatically depending the purpose of use as well as whos using it. In most cases the compound comprised of Tamoxifen Citrate will be used for on cycle side-effect prevention, Post Cycle Therapy (PCT) and by females for atestosterone boosting effect or as part of a physique competition preparation. In any case the average Nolvadex dosage will range from 10mg to 40mg and in most cases never exceed this mark. In order to determine the right Nolvadex dosage for you we only need to examine the three common points of use.
1) Female Nolvadex Dosage:
Tamoxifen Citrate can be an excellent performance enhancing tool for the female athlete as it has the ability to increase testosteroneproduction as well as bind estrogen. Many female athletes will opt for this testosterone boosting effect instead of anabolic steroids due to the possibility of virilization that many of them can bring about. More commonly is however the use by females in the physique sports competitions; not only bodybuilding but figure and bikini as well. Such use can promote a leaner and tighter looking physique and often be the difference in how well the athlete places. For most women the most common Nolvadex dosage will be at 10mg per day with very few ever exceeding 20mg per day and most will never need this much.
2) On Cycle Nolvadex Dosage:
For decades many performance enhancing athletes have supplemented with Tamoxifen Citrate while on cycle in order to protect againstGynecomastia (male breast enlargement.) The manner in-which it works is simple; Gyno as it is commonly known is brought on by an increase of estrogen in the body; this increase is caused by anabolic steroids that aromatize. As the excess estrogen exists it may then bind to the receptors in the chest causing Gyno. Fortunately a good 10mg Nolvadex dosage can often protect against this onset action. As estrogen buildup occurs Tamoxifen Citrate binds in the estrogens place preventing it from binding and causing Gyno. While 10mg will work many men will need a Nolvadex dosage of 20mg every day and when enough aromatizing steroids are taken there is no amount of Nolvadex on earth that will prevent it. If you are sensitive to Gynecomastia due to high doses or simply being sensitive by nature you will need to seek out aromatase inhibitors as they will be all that protects you.
3) Post Cycle Nolvadex Dosage:
PCT has been and will always be the most common period of Tamoxifen Citrate use and as such more will be interested in the correct Nolvadex dosage for this period beyond any other. The purpose of use during PCT is simple; to stimulate natural testosterone production that has been suppressed due to anabolic steroid use and more than likely tremendously so. For most men daily therapy will begin at 40mg per day, eventually dropping to 20mg per day until use is discontinued. The average man will need at least 4 weeks of total therapy with many men needing 6 total weeks if their steroid cycle was long and suppressive in nature. However long your PCT plan is a Nolvadex dosage of 40mg per day for the first half of the plan followed by a 20mg every day the final weeks will suffice.
5. Nolvadex Recipe:
Highest concentration made - 20mg/ml
Per 1 gram of Tamoxifen Citrate you will need:
9.8 ml's of PEG 600
39.2 ml's of 190 Proof Grain Alcohol
6. COA and HPLC:
|Product name||Tamoxifen citrate (Nolvadex)|
|Appearance||White crystalline powder|
|Identification||IR , UV conform||Conform|
|Loss on drying||<0.5ml||0.21ml|
|Residue on ignition||Not more than 0.2%||0.06ml|
|Iron||Not more than 0.005%||0.0018%|
|Heavy metals||Not more than 0.001%||0.0006%|
|Related substances||Total: Not more than 1.0% Individual: Not more than 0.5%||0.32% 0.14%|
|E-isomer||Not more than 0.3%||0.19%|
|Organic volatile impurities||Conforms||Conforms|
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