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CAS: | 98319-26-7 | MF: | C23H36N2O2 |
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MW: | 372.54 | Packing: | Foil Bag |
Appearance: | White Or White Crystalline Solid | Assay: | Above 99% |
High Light: | Synthetic Anabolic Steroids,Legal Synthetic Steroids |
Finasteride Powder Anabolic Legal Steroids 98319-26-7 For Treating Enlarged Prostate / Hair Loss
Description:
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used for the treatment of benign prostatic hyperplasia (enlarged prostate) and pattern hair loss. It is a type II and type III 5α-reductase inhibitor; 5α-reductase, an enzyme, converts testosterone to dihydrotestosterone (DHT).
Specifications:
Chemical name: Finasteride
English Synonyms: PROSCAR;PROSTIDE;N-(2-METHYL-2-PROPYL)-3-OXO-4-AZA-5ALPHA-ANDROST-1-ENE-17BETA-CARBOXAMIDE;MK-906;(5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta
CAS NO.: 98319-26-7
Assay: Above 99%
Molecular Formula: C23H36N2O2
Molecular Weight: 372.54
Packing: foil bag
Melting point: 250°C
Character: White or white crystalline solid.
Solubility: It is freely soluble in chloroform and in lower alcohol solvents, but is practically insoluble in water.
Usage: The drug can be very effective in reducing blood and dihydro testosterone within the prostate. Finasteride no affinity to the androgen receptor.
2D Structure:
COA:
Test Items | Specification | Test Results | |
Description | White crystalline powder | white powder | |
Specific rotation | -56°~-60° | -58.2° | |
Identification | IR | Matches with working standard | Complies |
HPLC | |||
Solubility | Freely soluble in chloroform and in alcohol; Very slightly soluble in water |
Conform | |
Heavy metals | ≤10ppm | <10ppm | |
Water | ≤0.3% | 0.22% | |
Residue on ignition | ≤0.1% | 0.05% | |
Relative material | Maximum impurities≤0.5% | 0.36% | |
Total impurities≤1.0% | 0.52% | ||
Assay | 98.5~101.0% | 99.68% | |
Conclusion | The specification conform with USP29 |
Medical Use:
1. Benign prostatic hyperplasia:
Physicians use finasteride for the treatment of BPH, informally known as an enlarged prostate. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow. It provides less symptomatic relief than alpha-1 blockers such as tamsulosin and symptomatic relief is slower in onset (six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment). Symptomatic benefits are mainly seen in those with prostate volume > 40 cm3. In long-term studies finasteride but not alpha-1 inhibitors reduce the risk of acute urinary retention (−57% at 4 years) and the need for surgery (−54% at 4 years). If the drug is discontinued, any therapeutic benefits reverse within about 6-8 months.
Finasteride works by blocking the conversion of the hormone testosterone to the more potent hormone dihydrotestosterone. It does this by blocking an enzyme called 5-alpha reductase. Dihydrotestosterone is partly responsible for making the prostate enlarge. Therefore, a reduced amount of dihydrotestosterone in the prostate causes it to shrink. This helps you to pass urine more easily.
2. Pattern hair loss:
Hair loss caused by male pattern baldness occurs when a hormone called DHT (dihydrotestosterone) prevents hair follicles from getting the vital nutrients they need to live. Finasteride blocks the production of DHT and thus protects the hair follicles that produce hair. Reducing DHT can stop and even reverse hair loss caused by male pattern baldness.
3. Off-label uses:
Finasteride is sometimes used in hormone replacement therapy for transgender women in combination with a form of estrogen due to its antiandrogen properties. However, little clinical research of finasteride use for this purpose has been conducted and evidence of efficacy is limited.
How to Take Finasteride:
Take finasteride exactly as your doctor tells you to. Take one 5 mg tablet each day.
You can take the tablet either before or after a meal, but try to take it at the same time of day each day. This will help you to remember to take your doses regularly.
If you forget to take a dose on time, take it when you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
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