CAS 171599-83-0 Bodybuilding Anabolic Steroids Drugs Sildenafil Viagra To Treat ED

CAS 171599-83-0 Bodybuilding Anabolic Steroids Drugs Sildenafil Viagra To Treat ED

Description:

Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

Specification:

Sildenafil citrate
CAS: 171599-83-0
Assay: 99% min.
Standard: USP32
Packing: 1kg/foil bag, 5kg/drum.
Delivery: Express courier.
MF: C28H38N6O11S
MW: 666.7
Character: White Solid.
MP:187-189°C
Usage: An orally active selective type 5 cGMP phosphodiesterase inhibitor. pharmaceutical material
Biological Activity: Orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC 50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro .

2D Structure:

Applications:

1. Treatment of ED:

If you are taking sildenafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity. Sildenafil usually should not be taken more than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take sildenafil less often. You can take sildenafil with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work.

2. Trearment of PAH:

If you are taking sildenafil to treat PAH, follow your doctor's directions and the guidelines in this paragraph. You will probably take sildenafil three times a day with or without food. Take sildenafil at around the same times every day, and space your doses about 4 to 6 hours apart.

If you are taking sildenafil for erectile dysfunction, your doctor will probably start you on an average dose of sildenafil and increase or decrease your dose depending on your response to the medication. Tell your doctor if sildenafil is not working well or if you are experiencing side effects.

If you are taking sildenafil for PAH, you should know that sildenafil controls PAH but does not cure it. Continue to take sildenafil even if you feel well. Do not stop taking sildenafil without talking to your doctor.

How Dose Sildenafil Work?

Erectile dysfunction (sometimes called impotence) means that you cannot get or maintain a proper erection. There are several causes, the most common being due to a narrowing of the arteries that take blood to the penis.

Sildenafil works by preventing the action of a chemical in your body, called phosphodiesterase type-5. This helps to widen (relax) blood vessels and improves the flow of blood to the penis following sexual stimulation. This helps to maintain an erection.

Before Taking Sildenafil:

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking sildenafil it is important that your doctor knows:

If you have any disease, injury or deformity of your penis.
If you have a heart condition, or blood vessel disease.
If you have had an eye condition causing loss of vision.
If you have low blood pressure or angina.
If you have any problems with the way your liver works or with the way your kidneys work.
If you have had a stroke or a heart attack.
If you have a condition which causes bleeding, such as a stomach ulcer.
If you have sickle cell disease.
If you have ever had bone marrow cancer or leukaemia.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines, and recreational drugs.
If you have ever had an allergic reaction to a medicine.

Dose of Sildenafil for ED:

It is intended to be taken before sexual activity - it is NOT for continuous daily use. You should take one tablet about an hour before you plan to have sex, although it may still be effective up to five hours after taking the tablet. You can take the tablet either before or after food but, if you have just eaten a large meal, it may take longer for it to work.

There are three strengths of sildenafil tablets: 25 mg, 50 mg and 100 mg. It is likely that you will be given the 50 mg strength tablet to begin with, but this may be changed subsequently depending upon how you react. Each time you collect a prescription, check to make sure it contains the strength of tablet you are expecting.

If you have been supplied with a brand of tablet called Nipatra, these are chewable tablets. Chew the tablet before you swallow it.
Do not take more than one dose of sildenafil in any 24-hour period.

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