Phenacetins ( fenacetina ) Pharmaceutical Intermediates Used as Antipyretic-Analgesic Phenacetin

1.Basic Info.

CAS:62-44 2
EINECS:200-533-0
Molecular Formula:C10H13NO2
Molecular Weight:179.22
Density:1.099 g/cm3
Melting Point:133-138ºC
Flash Point:355.1 °C at 760 mmHg
Storage Temperature:2-8°C
Refractive index:1.505 (20 C)
Solubility:0.076 g/100 mL
Appearance:white crystalline powder
Stability:Stable. Incompatible with strong oxidizing agents, strong acids.
Usage:Analgesic.
Synonyms:
1-acetamido-4-ethoxybenzene; para-Acetophenetidide; p-acetophenetidine; p-acetophenetide; p-acetphenetidin; paracetophentidin; p-Ethoxyacetanilide; 4'-ethoxyacetanilide; acet-p-phenalide; acet-p-phenetidin; aceto-para-phenalide; aceto-para-phenetidide; Acetophenetidine; acetophenetin; acetylphenetidin; coricidin; empirin compound; N-(4-ethoxyphenyl)-acetamide; N-Acetyl-4-ethoxyaniline; N-acetyl-p-phenetidine; phenacet; phenazetin; Phorazetim; pyraphen

2.COA

3.Phenacet/ Fenacetina Application:
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetis has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treatrheumatoid arthritis (subacute type) and intercostal neuralgia.

4.Phenacet/ Fenacetina Function:
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetins-Acetate not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetins-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.

5.Phenacet/ Fenacetina Storage:
Phenacetins should be Store in Cool and Dry Place.

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4.Injectable steroid.We offer melting powder into liquid service.And ship the liquid in special bottles.

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