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High Purity Local Anesthetic Drugs 4-Acetamidophenol / Paracetamol for Antipyretic , CAS 103-90-2
Product Details:
Payment & Shipping Terms:
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Detailed Product Description
| Product Name: | Paracetamol | Appearance: | White To Pale Yellow Crystalline Powder |
|---|---|---|---|
| CAS: | 103-90-2 | Sample: | Yes |
| High Light: | Local Anesthetic Agents,Injectable Local Anesthetics |
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Paracetamol
Basic Details:
Product Name: 4-Acetamidophenol
Synonyms: Paracetamol
CAS: 103-90-2
MF: C8H9NO2
MW: 151.16
EINECS: 203-157-5
mp: 168-172 °C(lit.)
density: 1.293 g/cm3
Fp: 11 °C
storage temp: Store at RT
Water Solubility: 14 g/L (20°C)
Appearance: Odorless white crystalline solid
Description:
This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and selectivity in the hypothalamus of the temperature regulating center, the synthesis of prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of its antipyretic effect similar to aspirin.
Paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).
Acetaminophen is the name adopted for this pharmacologic agent in the U. S. (USAN) and Japan; Paracetamol is approved in a variety of international venues.
Paracetamol is classified as a mild analgesic. It is commonly used for the relief of headaches and other minor aches and pains and is a major ingredient in numerous cold and flu remedies. In combination with opioid analgesics, paracetamol can also be used in the management of more severe pain such as post-surgical pain and providing palliative care in advanced cancer patients. Though paracetamol is used to treat inflammatory pain, it is not generally classified as an NSAID because it exhibits only weak anti-inflammatory activity.
Application:
Paracetamol is approved for reducing fever in people of all ages.
Paracetamol is used for the relief of pains associated with many parts of the body. It has analgesic properties comparable to those of aspirin, while its antiinflammatory effects are weaker. It is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern.
Paracetamol powder nutritional supplemen Mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics. Serine constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role.
Detection Result:
| Tests | Standards | Results | |
| Appearance | White or almost white ,crystalline powder. | White,crystalline powder. | |
| Identification | A:IR absorption | Complies | Complies |
| B:UV absorption | Complies | Complies | |
| C:TLC | Complies | Complies | |
| Melting point | 168~172C | 169.0~170.9C | |
| Water | Not more than0.5% | 0.08% | |
| Related substance | Impurity(chloroacetanilide)not more than 10 ppm | 2ppm | |
| Impurity K(4-aminophenol)not more than 50 ppm | 15 ppm | ||
| Impurity F(4-nitrophenol)not more than 0.05% | Not detected | ||
| any other impurity not more than 0.05% | 0.01% | ||
| Total of other impurities not more than 0.1% | 0.02% | ||
| Residue on ignition | Not more than 0.1% | 0.05% | |
| Chloride | Not more than 0.014% | Less than 0.014% | |
| Sulfate | Not more than 0.02% | Less than 0.02% | |
| Sulfide | Conforms | Conforms | |
| Heavy metals | Not more than 0.001% | Less than 0.001% | |
| Free p-aminophenol | Not more than 0.005% | Less than 0.005% | |
| Limit of P-chloroacetanilide | Not more than 0.001% | Less than 0.001% | |
| Readily carbonizable substances | Conforms | Conforms | |
| Residual solvents | Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% | 0.08% | |
| Assay(anhydrous basis) | 99.0~101.0% | 99.6% | |
| Conclusion: Complies with USP34 / BP2011 | |||
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1. Mixed container, we can mix different items in one container.
2. Quality control, before shipment, free sample for test. After shipment, keep sample for 3 years
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