Glucagon 1 29 Peptide Hormones Bodybuilding CAS16941-32-5 Promoting Insulin / Islet Somatostatin

Glucagon 1 29 Human Growth Hormone Peptide CAS16941-32-5 Promoting Insulin / Islet Somatostatin

Description

Glucagon is also known as anti insulin or insulin B. Glucagon is a promoting hormone catabolism, glucagon has very strong promoting glycogenolysis and gluconeogenesis, make blood sugar rise significantly, activation of liver cells phosphorylase, acceleration of glycogenolysis, glucagon can also activate lipases, promote fat decomposition, and can enhance fat acid oxidation, so that ketogenesis increase, in addition, the secretion of glucagon may promote insulin and islet somatostatin.

Specification

Glucagon(1-29)(Human)

Alias:Glucagon(pig),Bovineglucagon,Glucagon(Canisfamiliaris stomach),Glucagon(Mesocricetus auratus),Glucagon(Saimirisciureus),Glucagon(Xenopus aevis),Glucagon (dog pancreas),Glucagon (dog),Glucagon (human),Glucagon (ox), Glukagon Novo, Human glucagon

Cas No. : 16941-32-5

Molecular Formula : C153H225N43O49S

M.S :

Molecular Weight: 3482.75

Purity (HPLC) : 99.0%min.

Appearance: White powder

Single Impurity (HPLC): 0.5%max

Amino Acid Composition: ±10% of theoretical

Peptide Content (N%): >75.0%

Water Content(Karl Fischer): <8.0%

HCl Content (HPIC): <10.0%

Specific Rotation (20/D): -37.0~-47.0°(c=1 1%HAc

Grade : Pharmaceutical Grade

Storage: Closed, below 2 ~ 8℃ preservation

Application

1) Glucagon has very strong promoting glycogenolysis and gluconeogenesis, make the blood glucose increased significantly, 1mol/L hormone can make 3 x 106mol/L glucose from glycogen decomposed rapidly out. Glucagon by cAMP-PK system, the activation of hepatic cells accelerated glycogen phosphorylase, decomposition. Gluconeogenesis is enhanced because hormone accelerate amino acids into liver cells, and activate the enzyme of gluconeogenesis.

2) Glucagon also activates lipase, promote fat decomposition, and can enhance the oxidation of fatty acid, so that increased ketogenesis. The target organ of glucagon produced the metabolic effects of the liver, liver resection or interruption of hepatic blood flow, these effects disappeared.

3) In addition, the secretion of glucagon may promote insulin and islet somatostatin. Pharmacological doses of glucagon can make the content of cAMp in myocardial cells increased, myocardial contraction enhancement.

Payment & Shipping Terms