Female Viagra Flibanserin Sex Enhancement Medicine 99.5% Purity CAS 167933-07-5

Female Viagra Flibanserin Sex Enhancement Medicine 99.5% Purity CAS 167933-07-5

Flibanserin is a drug developed to treat hypoactive sexual desire disorder (HSDD) in women. Women with HSDD have a chronic lack of interest in sex that cannot be explained by another medical condition. HSDD is also accompanied by feelings of distress.
Sometimes, flibanserin is called the “female Viagra,” but that term isn’t quite accurate. Viagra is a drug used to treat erectile dysfunction in men and works by improving blood flow to the penis. In other words, it mainly works on the genitals. Flibanserin is different because it works on a woman’s brain.The brain is often considered a woman’s more important sexual organ. Much of her sexual response cycle originates in her brain.

1. Quick Details:

2. How Does It Work?

Flibanserin works on three important brain chemicals: dopamine, norepinephrine, and serotonin. These chemicals are neurotransmitters. They are responsible for sending signals between the brain and other parts of the body through the nervous system.

Dopamine and norepinephrine are involved with sexual excitement. However, serotonin contributes to sexual inhibition and may dampen sex drive. It is thought that if these chemicals are out of balance - if dopamine and norepinephrine levels are too low and/or serotonin levels are too high - a woman might feel less sexual desire.

Flibanserin works by raising levels of dopamine and norepinephrine while lowering levels of serotonin. In this way, chemicals that help promote sexual desire are increased and one that can suppress desire is decreased.

3. Description of Flibanserin:

Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three.

Flibanserin,The certainty of the estimate is low.The side effects of dizziness, sleepiness, and nausea occur about three to four times more often.

Flibanserin is a drug developed to treat hypoactive sexual desire disorder (HSDD) in women. Women with HSDD have a chronic lack of interest in sex that cannot be explained by another medical condition. HSDD is also accompanied by feelings of distress.

4. Fuction of Flibanserin :

Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had "satisfying sexual events". In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month. The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.

The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced a increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and a increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.

Researchers think that flibanserin restores some of the chemical imbalances that affect sexual desire disorders. Most people have heard of antidepressants known as selective serotonin reuptake inhibitors, like fluoxetine (Prozac). SSRIs can have negative sexual side effects, such as reduced libido or erectile dysfunction. This suggests that serotonin plays an important role in sexual desire and excitation. Flibanserin affects serotonin but in a different way than SSRIs. It stimulates one type of receptor while blocking another, and it also increases dopamine in the body. Dopamine is known to have positive effects on sexual health.

5. Sex Steroid Hormones Dosage:

(1) Recommended dosage is 100 mg taken once daily at bedtime.
(2) Taking it at night reduces the risk of sleepiness, low blood pressure, and fainting during waking hours.
(3) If your symptoms do not improve after 8 weeks of treatment, stop treatment and call your doctor.
(4) If a dose is missed at bedtime, take the next dose at bedtime the following day. Do not take a double
dose to make up for a missed one.

6. Why Is Flibanserin Such Big News?

Up to 40 percent of women report having sexual problems, and about 12 percent find the problems very bothersome. This equates to millions of women who suffer from female sexual dysfunction, the most common being hypoactive sexual desire.

Women are still in the shadows when it comes to talking about sexual dysfunction. They’ve been told for years that their only options are expensive therapies, including psychotherapy, hormones, and supplements. The FDA’s standard of approval for drugs to treat sexual dysfunction in women is significantly higher than for those to treat men's sexual health concerns.

Just like Viagra opened the door for men to talk about sexual health, the hope is that flibanserin will allow women to discuss this often highly distressing problem-and have an option for treatment. This is an important development for women and for those of us who treat them.

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