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|BP:||535.1 ºC At 760 MmHg||Density:||1.045g/cm3|
Low Estrogen Steroids,
Pharma Grade Steroids
Toremifene Citrate Fareston Anti Estrogen Steroids CAS 89778-27-8 For Anti-Cancer
Toremifene Citrate (Fareston), known in bodybuilding circles as "torem" , as a selective estrogen receptor modulator (SERM) derived from triphenylethylene,Toremifene is used in postmenopausal women to treat breast cancer that has spread to other parts of the body (metastatic breast cancer). It is usually used to treat cancer that needs estrogen, a female hormone, in order to grow (estrogen-receptor positive). Toremifene is a nonsteroidal antiestrogen that blocks the effects of estrogen in the breast tissue, thereby slowing or stopping the growth of cancer.
Product Name: Toremifene citrate
Synonyms: FC 1157a; Fareston; NK 622; NSC 613680
Molecular Formula: C26H28ClNO.C6H8O7
Molecular Weight: 598.09
Melting Point: 158-164 ºC
Boiling Point: 535.1 ºC at 760 mmHg
Refractive index: 1,416-1,418
storage temp: -20°C Freezer
half Life : around 5 days
Appearance: White or almost white powder
Usage: Originally developed to fight breast cancer, bodybuilders have used Fareston to successfully fight gynocomastia caused when testosterone converts to estrogen in the body and men grow breasts. This substance can be used for little else and other similar compounds, such as Nolvadex or Clomid, are much more effective in post-cycle-therapy.
|Description||White Crystalline Powder||white powder|
|Specific Rotation||+34~ +38°(C=2,in dioxane)||+36.3°|
|Loss On Drying||1.0%max in vacuum over P2O5 for 4h||0.26%|
|Residual Solvents||meets the requirements.||Conforms|
|Organic Volatile Impurities||meets the requirements.||Conforms|
|Conclusion||The specification conform with USP30 standard|
Toremifene Citrate was originally patented as Fareston by the Orion Corporation of Finland, and approved for the treatment of breast cancer in Europe in 1996. In September of 1999, Roberts Pharmaceutical Corporation was granted the rights to market the drug in the United States of America.
Usage of Toremifene Citrate and Other SERMs:
Toremifene citrate (Fareston) is yet another SERM, which means Toremifene citrate (Fareston) will display both estrogen antagonist / agonist properties in the body. This puts Toremifene citrate (Fareston) in the same category as Nolvadex and Clomid, the two most popular drugs in Toremifene citrate (Fareston)s category.
At the hypothalamus and pituitary, estrogen acts in cooperation with the male body’s negative feedback loop to send a signal to decrease the secretion of LH, and when LH secretion is lowered, so are natural testosterone levels. SERMs, like Fareston, possibly act as an estrogen antagonist in the hypothalamus and pituitary, in order to increase testosterone production. Thus, although it hasn’t been studied to any great degree, it’s highly likely that Fareston is capable of increasing testosterone in the same way that Nolvadex it, as it’s androgenicity:estrogenicity ratio is 5x that of Nolvadex. It may also be better than Nolvadex for reasons that are of particular interest to steroid using athletes and bodybuilders.
Fareston differs from Nolvadex in several ways, however- even though it’s very similar to it in others. Firstly, the risk of certain side effects (although relatively rare with Nolvadex) is actually quite a bit lower with Fareston. However unlikely these risks are in the first place, the risk of stroke, pulmonary embolism, and cataract is probably lower with Fareston than with Nolvadex. This is going to be of interest to people who have issues with “floaters” in their vision, which is sometimes caused by Nolvadex and Clomid, as this product may represent significantly less occular toxicity. It also differs slightly from Nolvadex in its potent with regards to improving lipid (cholesterol) profiles. In terms of improving bone mineral density, Fareston is roughly equal to Nolvadex.
Although anecdotal evidence on this compound is rare, bodybuilders who have already experimented with this stuff seem satisfied. In my estimation, it would seem to be a more potent and safer alternative to Nolvadex, for those who are worried about side effects. I’m also predicting that it may provide a greater increase in LH and therefore testosterone levels, in men when compared to Nolvadex (when an appropriate dose of each is utilized). This makes its use a strong possibility for PCT in the future, when studies on its ability to elevate testosterone is more fully studied and understood.
Toremifene is also agonistic to Estrogen receptors in other tissues in the body. This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.
Side effects are typically low with fareston, but can include:
Swelling of legs and hands
Food and Drug Interactions:
Toremifene may interact with grapefruit. Taking this drug with grapefruit or grapefruit juice may cause increased levels of toremifene in your body.
This drug may interact with other medicines. Tell your doctor and pharmacist about all the medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. The safety and use of dietary supplements and alternative diets are often not known. Using these might affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's help.
For bodybuilding purposes, a dose of 40-60mgs per day seems to be a good starting point. If the user is trying to fight existing gynecomastia (bitch tits), they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120mgs per day and then lower to 40-60mgs per day for 4-6 weeks.
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|Contact Person||Debbie Yu|