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|MW:||293.37||Appearance:||An Off-white Color Crystalline Powder|
|Storage:||Shading, Confined Preservation||Standard:||Enterprise Standard|
Low Estrogen Steroids,
Pharma Grade Steroids
Safe Medical Low Estrogen Steroids Hormones Raw Prohormone Powders
Arimidex (anastrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Arimidex is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).
Product Name: Anastrozole
CAS NO: 120511-73-1
Molecular formula: C17H19N5
Molecular weight: 293.37
Appearance: an off-white color crystalline powder
Storage: Shading, confined preservation
Drug Class: Anabolic Androgenic Steroid
Standard: Enterprise Standard
Usage: An aromatase inhibitor. Used as an antineoplastic raw materials.
Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.
|Description||White crystalline powder||Complies|
|Conform with standard IR
Conform with standard HPLC
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|
1. Use in Medicine:
Anastrozole was approved by the U.S. Food and Drug Administration (FDA) in January 1996, and it is commercialized by AstraZeneca under the brand name Arimidex. The drug is indicated for postmenopausal women who suffer from early-stage, hormone receptor positive (HR+) breast cancer and who were previously treated with other therapies, who suffer from locally advanced or metastatic breast cancer that is HR+ or hormone receptor unknown as a first-line therapy, or who suffer from advanced breast cancer that has gotten worse after treatment with tamoxifen citrate.
2. Use in Bodybuilding:
When a man uses anabolic androgenic steroids (AAS), certain compounds will aromatize into estrogen. The main culprits that will do this are all testosterone esters, such as: cypionate, enanthate, dianabol, deca durabolin, and less so Boldenone (EQ). If estrogen isn't inhibited by using an AI (aromatase inhibitor), then high-estrogen side effects can occur. The most well-known side effect is gynecomastia or what is known commonly as 'gyno', 'bitch tits' or 'man breasts'. A man may notice a lump forming within his breast(s) – or under the nipple area; if not treated quickly, this can require serious surgery to remove. The lesser known but very serious side effects are caused by water retention, which can give a bloated or 'full' look. Extra water weight to your body or face (commonly called “moon face for its round or full look) can ruin a nice physique by making a person look fat. Internally, carrying around extra water weight will strain the body’s lipids across the board. A person can expect a rise in blood pressure, heart strain, and loss in energy. Also, high estrogen can affect libido.
How Anastrozole works:
Hormones are substances produced naturally in the body. They act as chemical messengers and help control the activity of cells and organs. Hormonal therapies interfere with the way hormones are made or how they work in the body.
Many breast cancers rely on the hormone oestrogen to grow. This type of breast cancer is called oestrogen receptor-positive (ER positive) breast cancer.
After the menopause, oestrogen is no longer made in the ovaries. Instead, it’s made in the fatty tissues of the body. This happens when an enzyme called aromatase changes other hormones into oestrogen. Anastrozole is a drug called an aromatase inhibitor. It blocks this process and reduces the amount of oestrogen in the body.
Arimidex VS Tamoxifen:
The large ATAC (Arimidex, Tamoxifen Alone or in Combination) trial compared Arimidex to tamoxifen after surgery. The researchers wanted to know how the medicines worked by themselves as well as together to see which combination would be the best treatment for postmenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer. Based on the results of this trial, giving Arimidex and tamoxifen at the same time isn't recommended.
The ATAC study found that 5 years of Arimidex is better than 5 years of tamoxifen as the first hormonal therapy for postmenopausal women with early-stage, hormone-receptor-positive breast cancer. Arimidex is better than tamoxifen for:
1. increasing the time before the cancer comes back in those who experience recurrence
2. reducing the risk of the cancer spreading to other parts of the body
3. reducing the risk of a new cancer developing in the other breast
Arimidex VS Letrozole:
Arimidex side effects are not as harsh when compared to AI like letrozole, which has a host of side effects; the most common being erectile dysfunction. Although estrogen is known as a female hormone, men still need it in their bodies. For men, estrogen balances them hormonally and helps them gain muscle and strength. That's why letrozole, a harsh AI that kills almost all estrogen, isn't always the best to achieve hormonal balance on your cycle. On the other hand, this is where arimidex shines, as it is a gentle AI that won't crush your estrogen levels, so you can be more balanced.
Arimidex is usually taken once per day at the same time. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take Arimidex with or without food.
Some AAS users will not use an AI at first but they will have it on hand just in case. This isn't always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize (steroids turning into estrogen), taking arimidex at this point would be like trying to stop a car already in motion.
General dosages for men: 0.5mgs per day or every other day. Remember, it's steroid dose dependent.
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