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|CAS:||112809-51-5||Alias:||Femara, Letrozole, TROZET|
Estrogen Blocker Steroids,
Low Estrogen Steroids
Pharma Raw Materials Anti Estrogen Steroids Effective Letrozole Femara Powder
Letrozole (trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery, It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.
Product Name: Letrozole
Alias: Femara, Letrozole, TROZET
CAS NO: 112809-51-5
Molecular Formula: C17H11N5
Molecular Weight: 285.31
Character: White or light yellow crystal
Usage: Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer.
For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia.
It will also raise testosterone levels because of the lowered estrogen in the body.
|Appearance||White or off-white crystaline powder||White Crystalline powder|
|Solubility||Soluble in Chloroform;
Soluble in ethanol when heated
|ldentification||(1)Maximum absorption in
wavelength of 240 nm Minimum
absorption in wavelength of 215 nm
|(2)Infrared spectrum should
be in accordance the
dominant peak of contrast
|In accordance with the
dominant peak of contrast
|Loss on drying||≤1.0%||0.8%|
|Conclusion||Conforms Specifications of Enterprise Standard.|
1. Letrozole for Breast Cancer Treatment:
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
2. Letrozole for Infertility Treatment:
Letrozole is being used commonly as an infertility treatment. Letrozole is a recent addition to the drugs being used for fertility treatment. Fertility drugs are used often in infertility treatments. There are two situations in which fertility drugs may be useful. First, these drugs can be used to induce an egg to develop and be released in women who are not ovulating on their own. This is known as ovulation induction. Fertility drugs can also be used to increase the chances of pregnancy in women who are already ovulating. This is known as superovulation.
How Letrozole Works:
Letrozole lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. Letrozole can stop or slow the growth of these cancers. It can also reduce the chance of a breast cancer coming back after surgery.
Letrozole only works in women who have had their menopause. It is a type of drug called an aromatase inhibitor. After the menopause, women don’t produce oestrogen from their ovaries. But they still produce a small amount by using an enzyme called aromatase which turns other sex hormones called androgens into oestrogen. This change happens mainly in fatty tissue, muscle and the skin. Aromatase inhibitors block aromatase so that it can’t change the androgen into oestrogen.
How to Take Letrozole?
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about letrozole and a full list of the side-effects which you may experience from taking it.
Take one 2.5 mg tablet of letrozole each day, exactly as your doctor tells you to. Your dose will be printed on the label of the tablet pack to remind you.
You may take letrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time each day. This will help you to avoid missing any doses.
You can take the tablets before or after your meals.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
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