Yiwu Lingxi Import&export Co.,Ltd

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsLocal Anesthetic Drugs

Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine

Certification
Good quality Androgenic Anabolic Steroids for sales
Good quality Androgenic Anabolic Steroids for sales
Your packing are the best ! If you can not do it no one can.You are my unique supplier from now on!

—— John from Australia

As with previous orders, my purchase was processed and dispatched quickly and efficiently. Everything arrived safely and was well packaged. Product is also of good quality.

—— Andrew Barlow,United Kingdom

I was eagerly awaiting my package to arrive but it was delayed by a few days. I contacted the seller and they were very fast in responding and apologized for the shipping error. They have excellent customer service. My goods arrived in perfect condition and I am very happy with my purchase !

—— Jason M from Canada

Supplier was helpful and prompt via email when I had a few questions. Product arrived quickly. I am very satisfied with them and would be happy to work with them again.

—— Ken LaVetter,United States

I'm Online Chat Now

Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine

China Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine supplier
Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine supplier Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine supplier

Large Image :  Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine

Product Details:

Place of Origin: China
Brand Name: LSW
Certification: GMP,ISO9001,KOSHER
Model Number: 484-12-8

Payment & Shipping Terms:

Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Discreet disguised package or as required
Delivery Time: Within 24 hours after payment
Payment Terms: T/T, , MoneyGram,,Bitcoin
Supply Ability: Mass stock
Contact Now
Detailed Product Description
Express: TNT,DHL,Fedex, UPS, EMS, HKEMS, Etc. CAS Number: 484-12-8
Standard: In-house Standard Appearance: White Powder
Purity: 99.6 % Storage: -20°C
High Light:

Injectable Local Anesthetics

,

Local Anesthetic Powder

Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine

 

Description:

 

Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens. It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects.1 Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

Specifications:

Product Name: Common Cnidium Fruit P.E.;2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-; Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-; Osthol; Ostol; Ostole; 7-Methoxy-8-isopentenylcoumarin; 8-(3-Methyl-2-butenyl)herniarin; 7-Methoxy-8-(3-methyl-2-butenyl)-coumarin; NSC 31868; 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-buten-1-yl)-
Part Used: Fruit
Active Ingredients: Osthole
CAS No.: 484-12-8
Molecular Formula: C15H16O3
Molecular Weight: 244.29
Storage:-20°C
Specfication: Osthole>10%-98%
Appearance: Greenish Yellow or white fine powder
Test Method: HPLC
Function: Cnidium seed has been very commonly used in formulations designed to warm the Kidneys and strengthen Yang energy. It is primarily used for the purpose of overcoming sexual malaise and strengthening sexual potency. The classics repeatedly mention it as an aphrodisiac.
Packing Detail: Packed in paper-drums and two plastic-bags inside. Net Weight: 25kgs/drum. I.D.
Storage Situation: Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat.


2D Structure:

 

Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine


Benefits of Osthole:

Osthole benefit for fatty liver:
Osthole improves fat milk-induced fatty liver in rats: modulation of hepatic PPAR-alpha/gamma-mediated lipogenic gene expression.
Planta Med. 2007.
The objectives of this study were to determine the therapeutic effect of osthole, an active constituent isolated from Cnidium monnieri, in hyperlipidemic fatty liver rats and investigate the possible mechanism of the osthole treatment. Osthole exerts therapeutic effects on fat milk-induced fatty liver in rats, by regulating mRNA expression of the target genes of CYP7A, DGAT, L-FABP and FATP4 via increasing the PPARalpha/gamma mRNA expression.

Liver cancer:
Chemical aspects of coumarin compounds for the prevention of hepatocellular carcinomas.
Curr Med Chem Anti-Cancer Agents. 2005.
The normalization of plasma alanine aminotransferase (ALT) has been proved to be a strategy for preventing the development of hepatocellular carcinoma in hepatitis C virus (HCV)-infection. Glycyrrhizin, a plant medicine, normalizes plasma ALT and prevents HCC. However, glycyrrhizin is administered intravenously and thereby chemical which is effective on oral administration is required. Coumarin compounds are active components of herbs used for the treatment of various diseases. The ability of coumarin compounds to lower plasma ALT were examined using mice concanavalin A-induced hepatitis and mice anti-Fas antibody-induced hepatitis. We conclude that osthole will become a leading chemical for synthesizing a compound which prevents liver cancer on oral administration.

PLoS One. May 2012. Growth inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular carcinoma.

Mental effects:
Osthole improves aspects of spatial performance in ovariectomized rats.
Am J Chin Med. 2004.
. Osthole improved the performance deficit in ovariectomized rats. The action mechanism of the effects of osthole on performance deficits was related to the estrogen-like properties and activating the central cholinergic neuronal system.

Biol Pharm Bulletin. 2015. The Coumarin Derivative Osthole Stimulates Adult Neural Stem Cells, Promotes Neurogenesis in the Hippocampus, and Ameliorates Cognitive Impairment in APP/PS1 Transgenic Mice.

Pulmonary hypertension:
Eur Journal Pharmacology. 2013. Osthole relaxes pulmonary arteries through endothelial phosphatidylinositol 3-kinase/Akt-eNOS-NO signaling pathway in rats. Pulmonary arterial hypertension is a life-threatening disease lacking effective therapies. Osthole is a natural coumarin compound isolated from Angelica pubescens Maxim., which possesses hypotensive effect.

Osthole relaxes trachea:
The relaxant action of osthole isolated from Angelica pubescens in guinea-pig trachea.
Naunyn Schmiedebergs Archives Pharmacolology. 1994.
Osthole, theophylline and higher concentrations of nifedipine suppressed the contraction response curves of tracheal smooth muscle caused by carbachol, prostaglandin F2 alpha (PGF2 alpha), U46619 (thromboxane A2 analogue) and leukotriene C4 (LTC4) in a concentration-dependent manner. It is concluded that osthole exerts a non-specific relaxant effect on the trachealis by inhibiting the cAMP and cGMP phosphodiesterases.

How to Take?

Since there is no information on Osthole consumption in isolation, the best lead currently is the dose of Cnidium fruits or seeds used in Traditional Medicine; which is 6-15g of either fruit or seed.


Osthole CAS 484-12-8 Local Anesthetic Drugs High Purity Sex Enhancement Medicine


Our Advantage:

High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

 

How to Proceed an Order?

 

Step 1 When you intended to buy something, pls send me an inquiry by email, skype or whatsapp.
Step 2 I will reply you with a quotation as soon as I receive you inquiry.
Step 3 We will negotiate products, price, package, payment methods and so on.
Step 4 You arrange the payment.
Step 5 I will arrange the shipment after receiving you money.
Step 6 The tracking number and the picture of the parcel will be sent to you.
Step 7 Trace the tracking number on website until you receive the goods.
Step 8 If you have any questions about the goods, pls contact me, i will try my best to satisfy you.

 


 

Contact Details
Yiwu Lingxi Import&export Co.,Ltd

Contact Person: Yuki

Tel: +8618186442580

Send your inquiry directly to us (0 / 3000)