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|CAS Registry Number:||50-28-2||MF::||C18H24O2|
|Molecular Weight::||272.39||Appearance:||White Or Milky White Crystalline Powder|
|Purity:||99%||Shipping Method:||Air&Sea Transporation,Express|
Estrogen Blocker Steroids,
Pharma Grade Steroids
Estradiol is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it. Estradiol is a kind of estrogen, can promote and regulate the normal development of women's genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk.
USP Anti-Estrogen Estradiol CAS 50-28-2 Sex Hormone for Growth of Certain Bones
Synonyms: Estradiol, 50-28-2, steroid powder
CAS No.: 50-28-2
Molecular Weight: 272.39
Density: 1.17 g/cm3
Melting Point: 178-179 ° C(lit. )
Boiling Point: 445.917 ° C at 760 mmHg
Flash Point: 209.634 ° C
Purity: 99% min
Application: Pharmaceutical Intermediates
Appearance: White crystalline powder
Storage: Keep it under seal in cool and dark place
Transportation: BY UPS, FedEx, EMS, TNT, DHL.
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Injections of estradiol are sometimes given to treat symptoms like these. They can also be used to compensate for ovary failure or similar conditions in women, and some forms of it can treat symptoms caused by prostate cancer in men. When given to women, it is necessary for them to use an effective form of birth control, due to the high risk of complications and birth defects that would exist in the event of a pregnancy.
Despite a common belief to the contrary, estrogens are important for male reproductive health and development as well. Estradiol is produced by a certain type of cell in the testes, and evidence suggests that it may be responsible for preventing the spontaneous death of sperm cells. Elevated levels can have negative effects, including a lowered sperm count. Males who have genetic conditions involving the sex chromosomes, such as Klinefelter's Syndrome, often have higher-than-normal levels. While it is primarily a sex hormone, estradiol also has complex interactions with the liver, governing the production of certain proteins, including those responsible for blood clotting.
Fuction of Estradiol
As a sex hormone, E2 has several different functions in women’s fertility. First, it helps to build and protect the lining of the fallopian tubes, vagina, and uterus. This role is critical to get the embryo to attach to the uterine wall. Many women who experience fertility problems have low levels of estradiol. Second, E2 maintains the oocytes, or egg cells, in the ovary. Healthy oocytes lead to healthy embryos. Only the best oocyte is selected at each ovulation period to be released and possibly
As a tissue builder, E2 seems to help protect women from heart disease by raising the levels of HDL, the “good” cholesterol in the body. When hormone levels drop in postmenopausal women, their risk of heart disease increases. E2 also helps protect bone density in both men and women by participating in a messaging system that suppresses an overly rapid growth of immune cells in the bone. If more immune cells are allowed to grow, they can block calcium absorption in the bone. This is why men with lower levels of this hormone in their system have been found to be more susceptible to hip fractures.
Usual Adult Dose for Breast Cancer - Palliative
10 mg orally 3 times a day for at least 3 months. Estrogen therapy for breast cancer should be considered only for palliation in the treatment of metastatic disease in select patients
|Appearance||White crystalline powder|
|Characteristics||White or creamy white, crystalline powder||conform|
|Melting point||173 ~ 179°C||178~ 179°C|
|Assay||97 .0~ 103.0%||99.07%|
|Loss on drying||≤0.5%||0.21%|
|Related substances||total impurities ≤1.0%||Pass|
|any individual impurity ≤0.5%||Pass|
|Residual solvents||ethanol ≤0.5%||Pass|
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