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CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment

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CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment

China CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment supplier
CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment supplier CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment supplier CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment supplier

Large Image :  CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment

Product Details:

Place of Origin: China
Brand Name: Senwayer
Certification: USP,ISO9001
Model Number: 139110-80-8

Payment & Shipping Terms:

Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Foil bag with disguised package or as required
Delivery Time: 3-5 working days
Payment Terms: T/T, , MoneyGram,Bitcoin
Supply Ability: 100kg per week and mass stock
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Detailed Product Description
CAS: 139110-80-8 Assay: 99% Min
MF: C12H20N4O7 MW: 332.31
Usage 1: Antiviral Agents Usage 2: Enzyme Inhibitors
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CAS 139110-80-8 Antiviral Agents Zanamivir Hydrate For Viral Influenza Treatment

 

1. Quick Details:

 

Product name: Zanamivir Hydrate
Synonyms: ZANAMIVIR HYDRATE;ZANAMIVIR(FORR&DONLY);4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid;4-Guanidino-Neu5Ac2en;D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy- (9CI);GANA;GANA (inhibitor);GG 167
CAS: 139110-80-8
MF: C12H20N4O7
MW: 332.31
MP: 256° C
Assay: 99% min
Molar Mass: 350.325 g/mol
Solubility: In water, 18,000 mg/L at 25 ℃
Chemical Properties: White to off-white powder

 

2. Description:

 

Zanamivir is a sialic acid-analogue neuraminidase inhibitor with antiviral activity. Administered into the respiratory tract by aerosol inhalation, zanamivir selectively binds to and inhibits influenza A and B virus neuraminidase-mediated cleavage of sialic acid residues in host cell membrane-bound glycoprotein receptors for influenza viruses, preventing the release of progeny viruses from host cell surfaces and, so, further viral replication.

 

3. Therapeutic Uses:

 

Zanamivir is indicated for the treatment of uncomplicated acute illness due to influenza A virus in adults and children 7 years and older who have been symptomatic for no more than 2 days. Zanamivir must be started within 48 hours after the onset of influenza symptoms.

 

Zanamivir is indicated for the treatment of uncomplicated acute illness due to influenza B virus in adults and children 7 years and older who have been symptomatic for not more than 2 days. Zanamivir must be started with 48 hours after the onset of influenza symptoms.

 

Zanamivir is indicated for the prophylaxis of influenza A and B. Although not a substitute for influenza virus vaccine, use of zanamivir may be considered if the vaccine is not available, in conjunction with the vaccine late in the influenza season, before the vaccine has induced an immune response, or if there is not immune response to the vaccine.


3. Route of Elimination:

 

It is excreted unchanged in the urine with excretion of a single dose completed within 24 hours. Unabsorbed drug is excreted in the feces.Zanamivir is renally excreted as unchanged drug.

 

4. Mechanism of Action:

 

The proposed mechanism of action of zanamivir is via inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release. By binding and inhibiting the neuraminidase protein, the drug renders the influenza virus unable to escape its host cell and infect others.

 

5. Matters Needing Attention:

 

Zanamivir is not a substitute for annual vaccination with influenza virus vaccine inactivated or influenza virus vaccine live intranasal. Although antiviral agents used for treatment or prevention of influenza (amantadine, oseltamivir, rimantadine, zanamivir) may be used concomitantly with influenza virus vaccine inactivated if indicated, influenza virus vaccine live intranasal should not be administered until at least 48 hours after influenza antiviral agents are discontinued and these antiviral agents should not be administered until at least 2 weeks after administration of influenza virus vaccine live intranasal.

 

 

6. COA:

 

Items Tested Specification Result
Characters White or almost white crystalline powder Confirms
Assay (HPLC) 99.0--101.0% 99.8%
Loss on Drying Not more than 0.5% 0.16%
Residue on ignition Not more than 0.2% 0.06%

 

7. Our Adwantage:

 

High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity:>=99%
3) We are manufacturer and can provide high quality products with factory price.

 

Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate: >=99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

 

We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

If you have any question pls feel free to contact me via:

Email: export@senwayer.com
Whats-app:+86-18186442580
Wickr me:yukis8888
We-chat:+86-18186442580
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